转发 Eric Topol：癌症免疫疗法的加速发展令人瞩目。如今，疫苗已在最顽固的癌症中实现部分治愈或缓解……
Eric Topol 指出，癌症免疫疗法正加速发展，令人瞩目。目前，疫苗已在胰腺癌、黑色素瘤、胶质母细胞瘤、肾癌和三阴性乳腺癌等最顽固的癌症中实现部分治愈或缓解。详情请查看其新发布的 Ground Truths。
相关报道
Scientists have developed a nasal spray treatment that reversed key signs of brain aging in animal studies. The spray delivers a molecule that restores cellular waste-clearing processes in the brain, improving cognitive function in older mice. Researchers hope to advance the treatment to human clinical trials.
Scientists showed a one-time gene therapy can lower LDL cholesterol by up to 60% for over a year in monkeys, offering a potential alternative to daily statins for heart disease prevention.
Arc Institute has raised $2.1 billion and secured a Nobel Prize for its work on programmable biology and RNA medicine, aiming to move beyond incremental drug development toward a systematic "constellation" approach to curing previously untreatable diseases. The institute's model combines academic freedom with long-term funding to tackle fundamental biological challenges.
Pancreatic cancer is notoriously difficult to treat due to the dense, protective tissue surrounding tumors, but a new drug combination targeting a specific protein called KRAS may offer a breakthrough. Clinical trials show promising results in shrinking tumors and improving survival rates, potentially transforming the outlook for one of the deadliest cancers.
Colorectal cancer rates are increasing among younger adults, but the article urges caution in interpreting the trend, noting that absolute risk remains low and that the rise is partly due to improved detection and screening practices.